{"id":512,"date":"2026-10-25T12:13:31","date_gmt":"2026-10-25T11:13:31","guid":{"rendered":"https:\/\/purvival.com\/journal\/?post_type=bw_ingredient&p=512"},"modified":"2026-10-25T22:28:21","modified_gmt":"2026-10-25T21:28:21","slug":"n-acetyl-cysteine","status":"publish","type":"bw_ingredient","link":"https:\/\/purvival.com\/journal\/ingredients\/n-acetyl-cysteine\/","title":{"rendered":"N-ac\u00e9tyl-cyst\u00e9ine"},"content":{"rendered":"

Ce que c\u2019est<\/h2>\n

La N-ac\u00e9tyl-cyst\u00e9ine (NAC) est une forme de la cyst\u00e9ine, un acide amin\u00e9 soufr\u00e9 pr\u00e9sent dans les prot\u00e9ines de la viande, du poisson, des \u0153ufs ou des l\u00e9gumineuses. Le corps se sert de la cyst\u00e9ine pour fabriquer le glutathion, une petite mol\u00e9cule qui prot\u00e8ge les cellules de l\u2019oxydation. La NAC est un m\u00e9dicament ancien<\/a>, employ\u00e9 pour fluidifier le mucus des bronches et, \u00e0 l\u2019h\u00f4pital, en cas de surdosage de parac\u00e9tamol ; elle augmente la quantit\u00e9 de glutathion dans les cellules.<\/p>\n

Dans un essai chinois chez 1 006 patients atteints de bronchopneumopathie chronique obstructive (BPCO)<\/a>, 600 mg de NAC deux fois par jour pendant un an ont r\u00e9duit de 22 % le nombre de pouss\u00e9es de la maladie par rapport au placebo.<\/p>\n

Deux g\u00e9lules d\u2019H\u00e9puria apportent 250 mg de N-ac\u00e9tyl-cyst\u00e9ine, avec de la choline, du schisandra, du romarin, de la gentiane, du s\u00e9l\u00e9nium et du chrome.<\/p>\n","protected":false},"excerpt":{"rendered":"

Forme stable de la cyst\u00e9ine, un acide amin\u00e9 soufr\u00e9, employ\u00e9e comme m\u00e9dicament et en compl\u00e9ment.<\/p>\n","protected":false},"featured_media":2778,"template":"","meta":{"_bw_latin":"","_bw_synonyms":"ac\u00e9tylcyst\u00e9ine, NAC","_bw_brand":"","_bw_precautions":"","_bw_subtitle":"ac\u00e9tylcyst\u00e9ine (NAC)","_bw_studies_intro":"

Dans un essai d\u2019un an chez 1 006 patients atteints de BPCO mod\u00e9r\u00e9e \u00e0 s\u00e9v\u00e8re, 600 mg de NAC deux fois par jour ont r\u00e9duit les pouss\u00e9es de la maladie de 22 % par rapport au placebo (1,16 contre 1,49 par patient et par an), avec une tol\u00e9rance comparable \u00e0 celle du placebo (Zheng et al., 2014<\/a>). Une m\u00e9ta-analyse de 14 essais (2 856 patients) a confirm\u00e9 une baisse du risque de pouss\u00e9es, y compris \u00e0 600 mg par jour ou moins (Cai et al., 2026<\/a>).<\/p>","_bw_mention":"","_bw_studies":[{"resultat":"1,16 pouss\u00e9e de la maladie par patient et par an sous NAC contre 1,49 sous placebo, soit 22 % de moins ; la tol\u00e9rance \u00e9tait comparable \u00e0 celle du placebo.","type":"essai","population":"1 006 patients de 40 \u00e0 80 ans atteints de BPCO mod\u00e9r\u00e9e \u00e0 s\u00e9v\u00e8re","dose":"600 mg de NAC deux fois par jour","duree":"1 an","auteurs":"Zheng et al. (PANTHEON)","annee":"2014","revue":"The Lancet Respiratory Medicine","lien":"https:\/\/doi.org\/10.1016\/S2213-2600(13)70286-8","source":"publication","note":"R\u00e9sum\u00e9 PubMed 24621680 lu. 34 h\u00f4pitaux chinois, double aveugle. Financ\u00e9 par Hainan Zambon Pharmaceutical (fabricant de NAC). Risque relatif 0,78."},{"resultat":"Chez des patients atteints de BPCO, la NAC a r\u00e9duit le risque de pouss\u00e9es (risque relatif 0,87 ; IC 95 % 0,79 \u00e0 0,96) ; \u00e0 600 mg par jour ou moins, risque relatif 0,84 (0,73 \u00e0 0,97) ; pas plus d\u2019effets ind\u00e9sirables que dans les groupes t\u00e9moins.","type":"revue","population":"14 essais randomis\u00e9s, 2 856 patients atteints de BPCO","dose":"","duree":"","auteurs":"Cai et al.","annee":"2026","revue":"PeerJ","lien":"https:\/\/doi.org\/10.7717\/peerj.21448","source":"publication","note":"R\u00e9sum\u00e9 PubMed 42473447 lu. Les auteurs appellent \u00e0 des essais plus grands et mieux con\u00e7us."}],"_bw_documents":[],"_bw_claims":["__none__"],"_bw_logo":0,"_bw_logo_dark":false},"class_list":["post-512","bw_ingredient","type-bw_ingredient","status-publish","has-post-thumbnail","hentry"],"yoast_head":"\nN-ac\u00e9tyl-cyst\u00e9ine - Journal Purvival<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/purvival.com\/journal\/ingredients\/n-acetyl-cysteine\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"N-ac\u00e9tyl-cyst\u00e9ine - Journal Purvival\" \/>\n<meta property=\"og:description\" content=\"Forme stable de la cyst\u00e9ine, un acide amin\u00e9 soufr\u00e9, employ\u00e9e comme m\u00e9dicament et en compl\u00e9ment.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/purvival.com\/journal\/ingredients\/n-acetyl-cysteine\/\" \/>\n<meta property=\"og:site_name\" content=\"Journal Purvival\" \/>\n<meta property=\"article:modified_time\" content=\"2026-10-25T21:28:21+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/purvival.com\/journal\/wp-content\/uploads\/sites\/5\/2026\/10\/n-acetyl-cysteine.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1344\" \/>\n\t<meta property=\"og:image:height\" content=\"752\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/purvival.com\\\/journal\\\/ingredients\\\/n-acetyl-cysteine\\\/\",\"url\":\"https:\\\/\\\/purvival.com\\\/journal\\\/ingredients\\\/n-acetyl-cysteine\\\/\",\"name\":\"N-ac\u00e9tyl-cyst\u00e9ine - 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