{"id":541,"date":"2026-10-25T12:13:31","date_gmt":"2026-10-25T11:13:31","guid":{"rendered":"https:\/\/purvival.com\/journal\/?post_type=bw_ingredient&p=541"},"modified":"2026-10-25T22:28:21","modified_gmt":"2026-10-25T21:28:21","slug":"huperzia-serrata","status":"publish","type":"bw_ingredient","link":"https:\/\/purvival.com\/journal\/ingredients\/huperzia-serrata\/","title":{"rendered":"Huperzia serrata"},"content":{"rendered":"

Ce que c\u2019est<\/h2>\n

L\u2019huperzia (Huperzia serrata<\/em>) est une petite plante sans fleurs de la famille des lycopodiac\u00e9es, utilis\u00e9e en m\u00e9decine chinoise. On en extrait l\u2019huperzine A, un alcalo\u00efde qui freine la cholinest\u00e9rase<\/a>, l\u2019enzyme qui d\u00e9grade l\u2019ac\u00e9tylcholine, un messager chimique des neurones. Plusieurs m\u00e9dicaments de la maladie d\u2019Alzheimer agissent sur la m\u00eame enzyme.<\/p>\n

Une m\u00e9ta-analyse de 2013<\/a> regroupant 20 essais chez 1 823 personnes atteintes de la maladie d\u2019Alzheimer a trouv\u00e9 une am\u00e9lioration de la m\u00e9moire et des activit\u00e9s du quotidien sous huperzine A. Comme l\u2019huperzine A agit comme ces m\u00e9dicaments, parlez-en \u00e0 votre m\u00e9decin si vous suivez un traitement.<\/p>\n

Deux g\u00e9lules de Neuron 5 apportent 10 mg d\u2019extrait de feuilles d\u2019huperzia, titr\u00e9 \u00e0 100 \u00b5g d\u2019huperzine A, avec du bacopa BacoMind\u00ae, de la phosphatidyls\u00e9rine, de la crini\u00e8re de lion et de la choline.<\/p>\n","protected":false},"excerpt":{"rendered":"

Petite plante chinoise de la famille des lycopodes, sans fleurs, dont on extrait l\u2019huperzine A.<\/p>\n","protected":false},"featured_media":2762,"template":"","meta":{"_bw_latin":"Huperzia serrata","_bw_synonyms":"","_bw_brand":"","_bw_precautions":"","_bw_subtitle":"","_bw_studies_intro":"

Une m\u00e9ta-analyse de 20 essais chez 1 823 personnes atteintes de la maladie d\u2019Alzheimer a trouv\u00e9 de meilleurs scores de m\u00e9moire (MMSE) et d\u2019activit\u00e9s du quotidien sous huperzine A que sous placebo (Yang et al., 2013<\/a>). Chez des personnes avec des troubles cognitifs l\u00e9gers, une m\u00e9ta-analyse de 9 essais a aussi relev\u00e9 de meilleurs scores de quotient de m\u00e9moire et de MMSE que sous placebo (Huang et al., 2019<\/a>). Dans un essai de 210 patients, une analyse secondaire a montr\u00e9 qu\u2019\u00e0 400 \u00b5g deux fois par jour, le score cognitif s\u2019\u00e9tait am\u00e9lior\u00e9 de 2,3 points \u00e0 11 semaines (Rafii et al., 2011<\/a>).<\/p>","_bw_mention":"","_bw_studies":[{"resultat":"\u00c0 400 \u00b5g deux fois par jour, le score cognitif s\u2019est am\u00e9lior\u00e9 de 2,3 points \u00e0 11 semaines contre une baisse de 0,3 point sous placebo (analyse secondaire).","type":"essai","population":"210 personnes atteintes de maladie d\u2019Alzheimer l\u00e9g\u00e8re \u00e0 mod\u00e9r\u00e9e","dose":"200 ou 400 \u00b5g d\u2019huperzine A deux fois par jour","duree":"au moins 16 semaines","auteurs":"Rafii et al.","annee":"2011","revue":"Neurology","lien":"https:\/\/doi.org\/10.1212\/WNL.0b013e318216eb7b","source":"publication","note":"R\u00e9sum\u00e9 PubMed 21502597 lu. Crit\u00e8re principal non atteint \u00e0 200 \u00b5g, dit tel quel ; essai du r\u00e9seau public ADCS."},{"resultat":"Sur 20 essais, l\u2019huperzine A a am\u00e9lior\u00e9 par rapport au placebo les scores de m\u00e9moire (MMSE) \u00e0 8, 12 et 16 semaines et les activit\u00e9s du quotidien ; pas d\u2019effet ind\u00e9sirable grave rapport\u00e9.","type":"revue","population":"1 823 personnes atteintes de maladie d\u2019Alzheimer, 20 essais","dose":"","duree":"","auteurs":"Yang et al.","annee":"2013","revue":"PLoS One","lien":"https:\/\/doi.org\/10.1371\/journal.pone.0074916","source":"publication","note":"Revue syst\u00e9matique et m\u00e9ta-analyse, r\u00e9sum\u00e9 PubMed 24086396 lu. Essais majoritairement chinois."},{"resultat":"Par rapport au placebo, l\u2019huperzine A a augment\u00e9 les scores de quotient de m\u00e9moire (MQ) et de MMSE chez des personnes avec des troubles cognitifs l\u00e9gers. Les effets ind\u00e9sirables \u00e9taient l\u00e9gers.","type":"revue","population":"9 essais randomis\u00e9s, personnes avec des troubles cognitifs l\u00e9gers","dose":"","duree":"","auteurs":"Huang et al.","annee":"2019","revue":"Zhongguo Zhong Yao Za Zhi","lien":"https:\/\/doi.org\/10.19540\/j.cnki.cjcmm.20180925.008","source":"publication","note":"R\u00e9sum\u00e9 PubMed 30989926 lu (article en chinois, r\u00e9sum\u00e9 en anglais). M\u00e9ta-analyse (RevMan 5.3). Nombre de participants, doses et dur\u00e9es non pr\u00e9cis\u00e9s dans le r\u00e9sum\u00e9."}],"_bw_documents":[],"_bw_claims":["__none__"],"_bw_logo":0,"_bw_logo_dark":false},"class_list":["post-541","bw_ingredient","type-bw_ingredient","status-publish","has-post-thumbnail","hentry"],"yoast_head":"\nHuperzia serrata - Journal Purvival<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/purvival.com\/journal\/ingredients\/huperzia-serrata\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Huperzia serrata - Journal Purvival\" \/>\n<meta property=\"og:description\" content=\"Petite plante chinoise de la famille des lycopodes, sans fleurs, dont on extrait l\u2019huperzine A.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/purvival.com\/journal\/ingredients\/huperzia-serrata\/\" \/>\n<meta property=\"og:site_name\" content=\"Journal Purvival\" \/>\n<meta property=\"article:modified_time\" content=\"2026-10-25T21:28:21+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/purvival.com\/journal\/wp-content\/uploads\/sites\/5\/2026\/10\/huperzia-serrata.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1600\" \/>\n\t<meta property=\"og:image:height\" content=\"895\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/purvival.com\\\/journal\\\/ingredients\\\/huperzia-serrata\\\/\",\"url\":\"https:\\\/\\\/purvival.com\\\/journal\\\/ingredients\\\/huperzia-serrata\\\/\",\"name\":\"Huperzia serrata - 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