{"id":566,"date":"2026-10-25T12:13:32","date_gmt":"2026-10-25T11:13:32","guid":{"rendered":"https:\/\/purvival.com\/journal\/?post_type=bw_ingredient&p=566"},"modified":"2026-10-25T22:28:21","modified_gmt":"2026-10-25T21:28:21","slug":"acide-hyaluronique","status":"publish","type":"bw_ingredient","link":"https:\/\/purvival.com\/journal\/ingredients\/acide-hyaluronique\/","title":{"rendered":"Acide hyaluronique"},"content":{"rendered":"

Ce que c\u2019est<\/h2>\n

L\u2019acide hyaluronique, ou hyaluronane, est une longue cha\u00eene de sucres que le corps fabrique lui-m\u00eame. Il est pr\u00e9sent dans tous les tissus de soutien et les organes, dont la peau et le liquide des articulations ; la peau en contient \u00e0 peu pr\u00e8s la moiti\u00e9<\/a>. Sa viscosit\u00e9 et son pouvoir hydratant expliquent son emploi en m\u00e9decine, en cosm\u00e9tique et, au Japon surtout, en compl\u00e9ment alimentaire.<\/p>\n

Pris par la bouche, il a surtout \u00e9t\u00e9 \u00e9tudi\u00e9 sur la peau. Dans un essai ta\u00efwanais<\/a> chez 40 adultes de 35 \u00e0 64 ans, 120 mg par jour pendant 12 semaines ont att\u00e9nu\u00e9 les rides et am\u00e9lior\u00e9 l\u2019hydratation et l\u2019\u00e9lasticit\u00e9 de la peau par rapport \u00e0 un placebo. Un essai tch\u00e8que chez 150 adultes<\/a> a trouv\u00e9 des effets du m\u00eame ordre \u00e0 120 mg par jour, et des effets aussi \u00e0 60 mg.<\/p>\n

Une dose de 15 ml de PhysioCollagen apporte 14,25 mg d\u2019acide hyaluronique, avec 5 g de collag\u00e8ne de poisson hydrolys\u00e9, de la vitamine C et du mangan\u00e8se.<\/p>\n","protected":false},"excerpt":{"rendered":"

Longue cha\u00eene de sucres que le corps fabrique lui-m\u00eame, pr\u00e9sente surtout dans la peau et le liquide des articulations.<\/p>\n","protected":false},"featured_media":2713,"template":"","meta":{"_bw_latin":"","_bw_synonyms":"hyaluronate de sodium","_bw_brand":"","_bw_precautions":"","_bw_subtitle":"hyaluronate de sodium","_bw_studies_intro":"

Pris par la bouche, l\u2019acide hyaluronique a surtout \u00e9t\u00e9 \u00e9tudi\u00e9 pour la peau : dans un essai de 12 semaines chez 40 adultes, 120 mg par jour ont am\u00e9lior\u00e9 les rides, l\u2019hydratation et l\u2019\u00e9lasticit\u00e9 par rapport au placebo (Hsu et al., 2021<\/a>), et un essai chez 150 adultes europ\u00e9ens a trouv\u00e9 des effets du m\u00eame ordre \u00e0 120 mg, et des effets aussi \u00e0 60 mg (Dole\u010dkov\u00e1 et al., 2025<\/a>). Une m\u00e9ta-analyse de 7 essais contre placebo a conclu \u00e0 une am\u00e9lioration significative de l\u2019hydratation, de l\u2019\u00e9lasticit\u00e9 et de la profondeur des rides (Amin et al., 2025<\/a>).<\/p>","_bw_mention":"","_bw_studies":[{"resultat":"Les rides, l\u2019hydratation de la couche superficielle de la peau, la perte d\u2019eau \u00e0 travers la peau et l\u2019\u00e9lasticit\u00e9 se sont am\u00e9lior\u00e9es par rapport au placebo au bout de 12 semaines.","type":"essai","population":"40 adultes asiatiques de 35 \u00e0 64 ans en bonne sant\u00e9","dose":"120 mg d\u2019acide hyaluronique par jour","duree":"12 semaines","auteurs":"Hsu et al.","annee":"2021","revue":"Nutrients","lien":"https:\/\/doi.org\/10.3390\/nu13072220","source":"publication","note":"R\u00e9sum\u00e9 PubMed 34203487 lu. Trois auteurs salari\u00e9s de Kewpie (fabricant d\u2019acide hyaluronique)."},{"resultat":"\u00c0 120 mg par jour, l\u2019hydratation et l\u2019\u00e9lasticit\u00e9 de la peau ont augment\u00e9, la perte d\u2019eau, le s\u00e9bum et les rides du contour de l\u2019\u0153il ont diminu\u00e9 par rapport au placebo ; \u00e0 60 mg, des effets semblables ont \u00e9t\u00e9 observ\u00e9s.","type":"essai","population":"150 adultes europ\u00e9ens en bonne sant\u00e9","dose":"60 ou 120 mg de hyaluronate de sodium par jour","duree":"12 semaines","auteurs":"Dole\u010dkov\u00e1 et al.","annee":"2025","revue":"Scientific Reports","lien":"https:\/\/doi.org\/10.1038\/s41598-025-32758-5","source":"publication","note":"R\u00e9sum\u00e9 PubMed 41422283 lu. Auteurs salari\u00e9s de Contipro (fabricant) ; essai enregistr\u00e9 a posteriori sur ClinicalTrials.gov."},{"resultat":"Revue des travaux sur l\u2019acide hyaluronique aval\u00e9 : un essai contre placebo a montr\u00e9 une meilleure hydratation de la peau chez des personnes \u00e0 peau s\u00e8che ; une partie de la mol\u00e9cule absorb\u00e9e gagne la peau.","type":"revue","population":"\u00c9tudes chez l\u2019humain et l\u2019animal","dose":"","duree":"","auteurs":"Kawada et al.","annee":"2014","revue":"Nutrition Journal","lien":"https:\/\/doi.org\/10.1186\/1475-2891-13-70","source":"publication","note":"R\u00e9sum\u00e9 PubMed 25014997 lu. Revue narrative \u00e9crite par des chercheurs de Kewpie."},{"resultat":"La m\u00e9ta-analyse de 7 essais contre placebo a trouv\u00e9 des am\u00e9liorations significatives de l\u2019hydratation, de l\u2019\u00e9lasticit\u00e9 et de la profondeur des rides, avec une tendance \u00e0 l\u2019am\u00e9lioration pour la fermet\u00e9, le volume des rides et la perte d\u2019eau.","type":"revue","population":"7 essais randomis\u00e9s contre placebo sur l\u2019acide hyaluronique pris par la bouche","dose":"","duree":"","auteurs":"Amin et al.","annee":"2025","revue":"Journal of Drugs in Dermatology","lien":"https:\/\/doi.org\/10.36849\/jdd.8542","source":"publication","note":"R\u00e9sum\u00e9 PubMed 40911749 lu. Les auteurs signalent un \u00e9chantillon limit\u00e9 et de l\u2019h\u00e9t\u00e9rog\u00e9n\u00e9it\u00e9 entre les \u00e9tudes. \u00c0 conna\u00eetre : une autre m\u00e9ta-analyse (PubMed 40761858, 40 essais sur les compl\u00e9ments contre le photovieillissement) ne trouve pas de b\u00e9n\u00e9fice significatif de l\u2019acide hyaluronique ; non cit\u00e9e dans le r\u00e9sum\u00e9 de la page."}],"_bw_documents":[],"_bw_claims":["__none__"],"_bw_logo":0,"_bw_logo_dark":false},"class_list":["post-566","bw_ingredient","type-bw_ingredient","status-publish","has-post-thumbnail","hentry"],"yoast_head":"\nAcide hyaluronique - Journal Purvival<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/purvival.com\/journal\/ingredients\/acide-hyaluronique\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Acide hyaluronique - 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