{"id":1068,"date":"2025-01-06T05:21:18","date_gmt":"2025-01-06T04:21:18","guid":{"rendered":"https:\/\/purvival.com\/journal\/?p=1068"},"modified":"2026-10-26T20:08:14","modified_gmt":"2026-10-26T19:08:14","slug":"perilla-et-sante-du-foie-etudes-recentes","status":"publish","type":"post","link":"https:\/\/purvival.com\/journal\/perilla-et-sante-du-foie-etudes-recentes\/","title":{"rendered":"Perilla et sant\u00e9 du foie : ce que disent les \u00e9tudes"},"content":{"rendered":"<p>La <strong>Perilla frutescens<\/strong> est une plante utilis\u00e9e en m\u00e9decine asiatique, dont on emploie l\u2019huile de graines riche en ALA. Chez l\u2019humain, un essai de six mois a observ\u00e9 une baisse du cholest\u00e9rol total et du LDL sous p\u00e9rilla (<a href=\"https:\/\/doi.org\/10.2174\/1567205016666181212153720\">Kamalashiran et al., 2019<\/a>). Les points \u00e0 retenir sont les suivants.<\/p>\n<ul>\n<li>\n<strong>Principaux composants actifs<\/strong> : Acide alpha-linol\u00e9nique (ALA), acide rosmarinique, acide caf\u00e9ique.\n<\/li>\n<li>\n<strong>Pistes \u00e9tudi\u00e9es pour le foie<\/strong> :<\/p>\n<ul>\n<li>\nM\u00e9tabolisme des graisses, observ\u00e9 surtout chez l\u2019animal.\n<\/li>\n<li>\nR\u00e9ponse inflammatoire, \u00e9tudi\u00e9e en laboratoire.\n<\/li>\n<li>\nStress oxydatif, au stade pr\u00e9liminaire.\n<\/li>\n<\/ul>\n<\/li>\n<li>\n<strong>Pr\u00e9caution<\/strong> : la p\u00e9rilla est d\u00e9conseill\u00e9e aux femmes enceintes ; demandez l\u2019avis de votre m\u00e9decin si vous suivez un traitement.\n<\/li>\n<\/ul>\n<h3>Comparaison rapide avec d\u2019autres suppl\u00e9ments pour le foie<\/h3>\n<table>\n<thead>\n<tr>\n<th>Suppl\u00e9ment<\/th>\n<th>Compos\u00e9s actifs<\/th>\n<th>M\u00e9canisme d\u2019action<\/th>\n<th>Niveau de preuve clinique<\/th>\n<th>Profil de s\u00e9curit\u00e9<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Perilla<\/strong><\/td>\n<td>ALA, acide rosmarinique<\/td>\n<td>Acide alpha-linol\u00e9nique, compos\u00e9 de l\u2019huile de graines<\/td>\n<td><a href=\"https:\/\/doi.org\/10.3390\/foods10051130\">\u00c9tudes humaines sur le potentiel antioxydant du sang<\/a><\/td>\n<td>D\u00e9conseill\u00e9 aux femmes enceintes<\/td>\n<\/tr>\n<tr>\n<td><strong>Chardon-Marie<\/strong><\/td>\n<td>Silymarine<\/td>\n<td>Soutient la sant\u00e9 du foie<\/td>\n<td><a href=\"https:\/\/doi.org\/10.1007\/s12325-020-01251-y\">\u00c9tudes cliniques chez des patients atteints de maladie du foie<\/a><\/td>\n<td>Tr\u00e8s bien tol\u00e9r\u00e9e<\/td>\n<\/tr>\n<tr>\n<td><strong>Curcuma<\/strong><\/td>\n<td>Curcumine<\/td>\n<td>Soutient le foie et la fonction biliaire<\/td>\n<td><a href=\"https:\/\/doi.org\/10.1136\/bmjebm-2022-112231\">\u00c9tudes humaines sur la digestion<\/a><\/td>\n<td>D\u00e9conseill\u00e9 en cas de calculs biliaires ou de maladie du foie (Agence europ\u00e9enne des m\u00e9dicaments)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Consultez un professionnel de sant\u00e9 avant d\u2019int\u00e9grer un nouveau suppl\u00e9ment.<\/p>\n<h2>R\u00e9sultats des recherches sur la Perilla et la sant\u00e9 du foie<\/h2>\n<h3>Effets protecteurs de la Perilla sur le foie<\/h3>\n<p>Pour la Perilla, les chercheurs s\u2019int\u00e9ressent au m\u00e9tabolisme des graisses et \u00e0 la r\u00e9ponse inflammatoire. Nous d\u00e9taillons ce second point dans notre article sur la <a href=\"\/journal\/luteoline-dans-la-perilla-un-anti-inflammatoire-naturel\/\">lut\u00e9oline de la p\u00e9rilla<\/a>.<\/p>\n<p>Notre compl\u00e9ment <a href=\"https:\/\/purvival.com\/products\/perilla\">P\u00e9rilla<\/a> apporte, pour 2 capsules par jour, 2 000 mg d\u2019huile de graines de p\u00e9rilla riche en ALA. Il se prend \u00e0 raison de 2 capsules par jour. Il est d\u00e9conseill\u00e9 aux femmes enceintes.<\/p>\n<h3>M\u00e9canismes d&rsquo;action de la Perilla sur le foie<\/h3>\n<p>Les chercheurs \u00e9tudient son action sur le stockage des graisses, sur les cytokines de l\u2019inflammation et sur le stress oxydatif.<\/p>\n<h3>\u00c9tudes r\u00e9centes sur la Perilla et la sant\u00e9 h\u00e9patique<\/h3>\n<p>Un essai de six mois chez 182 patients atteints de d\u00e9mence l\u00e9g\u00e8re \u00e0 mod\u00e9r\u00e9e a observ\u00e9 une baisse du cholest\u00e9rol total et du LDL dans le groupe p\u00e9rilla, sans effet ind\u00e9sirable sur les reins, le foie ou la glyc\u00e9mie (<a href=\"https:\/\/doi.org\/10.2174\/1567205016666181212153720\">Kamalashiran et al., 2019<\/a>).<\/p>\n<p>Voici un r\u00e9sum\u00e9 des principaux r\u00e9sultats issus des \u00e9tudes sur la Perilla et ses effets sur le foie :<\/p>\n<table>\n<thead>\n<tr>\n<th>Aspect \u00e9tudi\u00e9<\/th>\n<th>R\u00e9sultats observ\u00e9s<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>M\u00e9tabolisme des graisses<\/td>\n<td>Pistes chez l\u2019animal, \u00e0 confirmer<\/td>\n<\/tr>\n<tr>\n<td>R\u00e9ponse inflammatoire du foie<\/td>\n<td>Pistes en laboratoire, \u00e0 confirmer<\/td>\n<\/tr>\n<tr>\n<td>Protection contre le stress oxydatif<\/td>\n<td>Donn\u00e9es pr\u00e9liminaires<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Comparaison de la Perilla avec d&rsquo;autres suppl\u00e9ments pour la sant\u00e9 du foie<\/h2>\n<p>Le chardon-Marie soutient la sant\u00e9 du foie : chez des patients atteints de st\u00e9atoh\u00e9patite non alcoolique, la fibrose du foie <a href=\"https:\/\/doi.org\/10.1016\/j.cgh.2017.04.016\">a recul\u00e9 d\u2019au moins un stade chez 22 % des patients sous silymarine, contre 6 % sous placebo<\/a> (voir notre <a href=\"\/journal\/silymarine-detox-hepatique-guide\/\">guide sur la silymarine et la d\u00e9tox h\u00e9patique<\/a>).<\/p>\n<table>\n<thead>\n<tr>\n<th>Suppl\u00e9ment<\/th>\n<th>Compos\u00e9s actifs<\/th>\n<th>M\u00e9canisme d&rsquo;action<\/th>\n<th>Niveau de preuve clinique<\/th>\n<th>Profil de s\u00e9curit\u00e9<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Perilla<\/strong><\/td>\n<td>Acide alpha-linol\u00e9nique, Acide rosmarinique<\/td>\n<td>Acide alpha-linol\u00e9nique de l\u2019huile de graines<\/td>\n<td><a href=\"https:\/\/doi.org\/10.2174\/1567205016666181212153720\">Essai chez 182 patients<\/a><\/td>\n<td>D\u00e9conseill\u00e9 aux femmes enceintes<\/td>\n<\/tr>\n<tr>\n<td><strong>Chardon-Marie<\/strong><\/td>\n<td>Silymarine<\/td>\n<td>Soutient la sant\u00e9 du foie<\/td>\n<td><a href=\"https:\/\/doi.org\/10.1007\/s12325-020-01251-y\">\u00c9tudes cliniques chez des patients atteints de maladie du foie<\/a><\/td>\n<td>Tr\u00e8s bien tol\u00e9r\u00e9e<\/td>\n<\/tr>\n<tr>\n<td><strong>Curcuma<\/strong><\/td>\n<td>Curcumine<\/td>\n<td>Soutient le foie et la fonction biliaire<\/td>\n<td><a href=\"https:\/\/doi.org\/10.1136\/bmjebm-2022-112231\">\u00c9tudes humaines sur la digestion<\/a><\/td>\n<td>D\u00e9conseill\u00e9 en cas de calculs biliaires ou de maladie du foie (Agence europ\u00e9enne des m\u00e9dicaments)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>D\u2019autres plantes sont \u00e9tudi\u00e9es pour le foie, comme l\u2019artichaut : voir <a href=\"\/journal\/artichaut-et-foie-ce-que-dit-la-science\/\">artichaut et foie, ce que dit la science<\/a>.<\/p>\n<h2>\n<a href=\"https:\/\/purvival.com\/\">Purvival<\/a> : Des Compl\u00e9ments Naturels Fiables<\/h2>\n<p><img decoding=\"async\" alt=\"Purvival\" src=\"https:\/\/purvival.com\/journal\/wp-content\/uploads\/sites\/5\/2025\/01\/purvival.com-e186bec3645a834e12da886192958fe7.jpg\">Purvival propose des compl\u00e9ments \u00e0 base de plantes, dont des programmes de d\u00e9toxification qui associent des plantes comme le chardon-Marie, le curcuma et l\u2019artichaut.<\/p>\n<table>\n<thead>\n<tr>\n<th>Atout<\/th>\n<th>Avantage<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Fabriqu\u00e9 en France<\/strong><\/td>\n<td>Produits fabriqu\u00e9s en France<\/td>\n<\/tr>\n<tr>\n<td><strong>Ingr\u00e9dients d&rsquo;origine naturelle<\/strong><\/td>\n<td>Ingr\u00e9dients issus de plantes<\/td>\n<\/tr>\n<tr>\n<td><strong>Validation par la science<\/strong><\/td>\n<td>Formulations qui s\u2019appuient sur des \u00e9tudes publi\u00e9es<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Le Diagnoscope de Purvival vous aide \u00e0 choisir parmi les compl\u00e9ments de la gamme selon vos besoins.<\/p>\n<h2>Conclusion et Perspectives de Recherche<\/h2>\n<p>Nous avons r\u00e9uni les donn\u00e9es disponibles sur la Perilla : un essai de six mois chez 182 patients et des mesures du potentiel antioxydant du sang. Les travaux \u00e0 venir portent sur les points suivants. Les femmes enceintes ne doivent pas prendre de p\u00e9rilla.<\/p>\n<table>\n<thead>\n<tr>\n<th>Axes de Recherche<\/th>\n<th>Objectifs<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Effets \u00e0 long terme<\/td>\n<td>\u00c9tudier l&rsquo;impact d&rsquo;une consommation prolong\u00e9e sur la sant\u00e9 du foie<\/td>\n<\/tr>\n<tr>\n<td>Interactions m\u00e9dicamenteuses<\/td>\n<td>Identifier les interactions possibles avec des traitements courants ; en attendant, demandez conseil \u00e0 votre m\u00e9decin si vous suivez un traitement<\/td>\n<\/tr>\n<tr>\n<td>Dosages optimaux<\/td>\n<td>D\u00e9finir les quantit\u00e9s adapt\u00e9es \u00e0 chacun<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Consultez un professionnel de sant\u00e9 avant d&rsquo;envisager une suppl\u00e9mentation. La p\u00e9rilla est d\u00e9conseill\u00e9e aux femmes enceintes.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Perilla et foie : ce que montrent les \u00e9tudes, surtout animales, ses composants, la comparaison avec le chardon-Marie et le curcuma, et les pr\u00e9cautions.<\/p>\n","protected":false},"author":4,"featured_media":1069,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-1068","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-detox-foie"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Perilla et sant\u00e9 du foie : ce que disent les \u00e9tudes<\/title>\n<meta name=\"description\" content=\"Perilla et foie : ce que montrent les \u00e9tudes, surtout animales, ses composants, la comparaison avec le chardon-Marie et le 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